Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors

Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors

Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%–27% may attempt suicide at least once in their life. We report the case of a patient who presented severe obsessive-compul...

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Main Authors: Maria S Signorelli, Carmen Concerto, Eliana Battaglia, Maria C Costanzo, Fortunato Battaglia, Eugenio Aguglia
Format: Article
Language:English
Published: SAGE Publishing 2014-12-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X14561778
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spelling doaj-6cba32effc5e42199ec2c6ac3b5f22e72020-11-25T03:24:17ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2014-12-01210.1177/2050313X1456177810.1177_2050313X14561778Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviorsMaria S Signorelli0Carmen Concerto1Eliana Battaglia2Maria C Costanzo3Fortunato Battaglia4Eugenio Aguglia5Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, ItalyDepartment of Interprofessional Health Sciences and Health Administration, Seton Hall University, South Orange, NJ, USAPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, ItalyPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, ItalyDepartment of Interprofessional Health Sciences and Health Administration, Seton Hall University, South Orange, NJ, USAPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, ItalyObsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%–27% may attempt suicide at least once in their life. We report the case of a patient who presented severe obsessive-compulsive disorder symptoms and attempted suicide ingesting 25 tablets of fluoxetine (20 mg). The patient was treated with venlafaxine and agomelatine and showed improvement of obsessive symptoms and suicidal ideation. Future studies are needed to investigate this treatment regime in large cohorts of obsessive-compulsive disorder patients with suicidal ideation.https://doi.org/10.1177/2050313X14561778
collection DOAJ
language English
format Article
sources DOAJ
author Maria S Signorelli
Carmen Concerto
Eliana Battaglia
Maria C Costanzo
Fortunato Battaglia
Eugenio Aguglia
spellingShingle Maria S Signorelli
Carmen Concerto
Eliana Battaglia
Maria C Costanzo
Fortunato Battaglia
Eugenio Aguglia
Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
SAGE Open Medical Case Reports
author_facet Maria S Signorelli
Carmen Concerto
Eliana Battaglia
Maria C Costanzo
Fortunato Battaglia
Eugenio Aguglia
author_sort Maria S Signorelli
title Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
title_short Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
title_full Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
title_fullStr Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
title_full_unstemmed Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
title_sort venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors
publisher SAGE Publishing
series SAGE Open Medical Case Reports
issn 2050-313X
publishDate 2014-12-01
description Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%–27% may attempt suicide at least once in their life. We report the case of a patient who presented severe obsessive-compulsive disorder symptoms and attempted suicide ingesting 25 tablets of fluoxetine (20 mg). The patient was treated with venlafaxine and agomelatine and showed improvement of obsessive symptoms and suicidal ideation. Future studies are needed to investigate this treatment regime in large cohorts of obsessive-compulsive disorder patients with suicidal ideation.
url https://doi.org/10.1177/2050313X14561778
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