Markers of breast cancer stromal fibroblasts in the primary tumour site associated with lymph node metastasis: a systematic review including our case series

Markers of breast cancer stromal fibroblasts in the primary tumour site associated with lymph node metastasis: a systematic review including our case series

CAFs (cancer-associated fibroblasts), the most abundant cell type in breast cancer stroma, produce a plethora of chemokines, growth factors and ECM (extracellular matrix) proteins, that may contribute to dissemination and metastasis. Axillary nodes are the first metastatic site in breast cancer; ho...

Full description

Bibliographic Details
Main Authors: Maria Aparecida Azevedo Koike Folgueira, Simone Maistro, Maria Lucia Hirata Katayama, Rosimeire Aparecida Roela, Fiorita Gonzales Lopes Mundim, Suely Nanogaki, Geertruida H. de Bock, M. Mitzi Brentani
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-12-01
Series:Bioscience Reports
Subjects:
breast cancer
cancer-associated fibroblasts
caveolin 1
lymph node metastasis
MMP13
podoplanin
Online Access:http://www.bioscirep.org/bsr/033/e085/bsr033e085.htm

Internet

http://www.bioscirep.org/bsr/033/e085/bsr033e085.htm

Similar Items