Mechanisms underlying CD4+ Treg immune regulation in the adult: from experiments to models

Mechanisms underlying CD4+ Treg immune regulation in the adult: from experiments to models

To maintain immunological balance the organism has to be tolerant to self while remaining competent to mount an effective immune response against third-party antigens. An important mechanism of this immune regulation involves the action of regulatory T-cell (Tregs). In this mini-review, we discuss s...

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Bibliographic Details
Main Authors: Marta eCaridade, Luis eGraca, Ruy M. Ribeiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
tolerance
regulation
Mathematical Models
Tregs
CD4-blockade
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00378/full

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