Zinc Status and Febrile Seizures: Results from a Cross-sectional Study
Objective To estimate the serum zinc levels in children under the age of 5 years with febrile seizures and febrile children without seizures Materials and Methods In this cross-sectional study from 2017 to 2018, 40 children with febrile seizures (simple and complex) were taken as cases. Forty age-...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-09-01
|
Series: | Journal of Neurosciences in Rural Practice |
Subjects: | |
Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1715992 |
id |
doaj-6d0d91806b594c3ab65b3191b3b710e6 |
---|---|
record_format |
Article |
spelling |
doaj-6d0d91806b594c3ab65b3191b3b710e62021-04-02T13:14:24ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552020-09-01110459760010.1055/s-0040-1715992Zinc Status and Febrile Seizures: Results from a Cross-sectional StudyJanani Arul0Peter Prasanth Kumar Kommu1Ananthanarayanan Kasinathan2Lopamudhra Ray3Lalitha Krishnan4Department of Pediatrics, Pondicherry Institute of Medical Sciences, Puducherry, IndiaDepartment of Pediatrics, Pondicherry Institute of Medical Sciences, Puducherry, IndiaDepartment of Pediatrics, Pondicherry Institute of Medical Sciences, Puducherry, IndiaDepartment of Biochemistry, Pondicherry Institute of Medical Sciences, Puducherry, IndiaDepartment of Pediatrics, Pondicherry Institute of Medical Sciences, Puducherry, IndiaObjective To estimate the serum zinc levels in children under the age of 5 years with febrile seizures and febrile children without seizures Materials and Methods In this cross-sectional study from 2017 to 2018, 40 children with febrile seizures (simple and complex) were taken as cases. Forty age- and sex-matched febrile children without convulsions were recruited as controls. Serum zinc estimates were analyzed using a spectrophotometer (Biolis 50i–Autoanalyzer). Statistical Analysis The demographic variables and serum zinc estimates were analyzed using the Mann–Whitney test. The odds ratio was used to calculate the association of zinc deficiency in febrile seizures; 5% level of significance was considered. Results The mean serum concentrations of zinc in the cases and controls were 83.8 ± 33.1 μg/dL and 116.3 ± 30.3 μg/dL, respectively (p = 0.002). Hypozincemia defined by “a serum zinc level of less than 63 μg/dL” was found in 12 (30%) cases and 2(5%) controls with an odds ratio of 8:1. Conclusion Children with febrile seizures had significantly reduced concentrations of zinc in the serum.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1715992zincfebrile seizuresepilepsychildren |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Janani Arul Peter Prasanth Kumar Kommu Ananthanarayanan Kasinathan Lopamudhra Ray Lalitha Krishnan |
spellingShingle |
Janani Arul Peter Prasanth Kumar Kommu Ananthanarayanan Kasinathan Lopamudhra Ray Lalitha Krishnan Zinc Status and Febrile Seizures: Results from a Cross-sectional Study Journal of Neurosciences in Rural Practice zinc febrile seizures epilepsy children |
author_facet |
Janani Arul Peter Prasanth Kumar Kommu Ananthanarayanan Kasinathan Lopamudhra Ray Lalitha Krishnan |
author_sort |
Janani Arul |
title |
Zinc Status and Febrile Seizures: Results from a Cross-sectional Study |
title_short |
Zinc Status and Febrile Seizures: Results from a Cross-sectional Study |
title_full |
Zinc Status and Febrile Seizures: Results from a Cross-sectional Study |
title_fullStr |
Zinc Status and Febrile Seizures: Results from a Cross-sectional Study |
title_full_unstemmed |
Zinc Status and Febrile Seizures: Results from a Cross-sectional Study |
title_sort |
zinc status and febrile seizures: results from a cross-sectional study |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2020-09-01 |
description |
Objective To estimate the serum zinc levels in children under the age of 5 years with febrile seizures and febrile children without seizures
Materials and Methods In this cross-sectional study from 2017 to 2018, 40 children with febrile seizures (simple and complex) were taken as cases. Forty age- and sex-matched febrile children without convulsions were recruited as controls. Serum zinc estimates were analyzed using a spectrophotometer (Biolis 50i–Autoanalyzer).
Statistical Analysis The demographic variables and serum zinc estimates were analyzed using the Mann–Whitney test. The odds ratio was used to calculate the association of zinc deficiency in febrile seizures; 5% level of significance was considered.
Results The mean serum concentrations of zinc in the cases and controls were 83.8 ± 33.1 μg/dL and 116.3 ± 30.3 μg/dL, respectively (p = 0.002). Hypozincemia defined by “a serum zinc level of less than 63 μg/dL” was found in 12 (30%) cases and 2(5%) controls with an odds ratio of 8:1.
Conclusion Children with febrile seizures had significantly reduced concentrations of zinc in the serum. |
topic |
zinc febrile seizures epilepsy children |
url |
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1715992 |
work_keys_str_mv |
AT jananiarul zincstatusandfebrileseizuresresultsfromacrosssectionalstudy AT peterprasanthkumarkommu zincstatusandfebrileseizuresresultsfromacrosssectionalstudy AT ananthanarayanankasinathan zincstatusandfebrileseizuresresultsfromacrosssectionalstudy AT lopamudhraray zincstatusandfebrileseizuresresultsfromacrosssectionalstudy AT lalithakrishnan zincstatusandfebrileseizuresresultsfromacrosssectionalstudy |
_version_ |
1721565696514588672 |