Serum interleukin-18 levels are associated with physical activity in Japanese men.

Serum interleukin-18 levels are associated with physical activity in Japanese men.

<h4>Objective</h4>To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men.<h4>Methods</h4>A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body co...

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Bibliographic Details
Main Authors: Kanae Oda, Nobuyuki Miyatake, Noriko Sakano, Takeshi Saito, Motohiko Miyachi, Izumi Tabata, Takeyuki Numata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349077/?tool=EBI
Description
Summary:<h4>Objective</h4>To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men.<h4>Methods</h4>A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated.<h4>Results</h4>Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors.<h4>Conclusion</h4>Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.
ISSN:1932-6203

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