ZNF507 affects TGF-β signaling via TGFBR1 and MAP3K8 activation in the progression of prostate cancer to an aggressive state

ZNF507 affects TGF-β signaling via TGFBR1 and MAP3K8 activation in the progression of prostate cancer to an aggressive state

Abstract Background The progression of prostate cancer (PC) to the highly aggressive metastatic castration-resistant prostate cancer (mCRPC) or neuroendocrine prostate cancer (NEPC) is a fatal condition and the underlying molecular mechanisms are poorly understood. Here, we identified the novel tran...

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Bibliographic Details
Main Authors: Wookbong Kwon, Seong-Kyoon Choi, Daehwan Kim, Hyeon-Gyeom Kim, Jin-Kyu Park, Jee Eun Han, Gil-Jae Cho, Sungho Yun, Wookyung Yu, Se-Hyeon Han, Yun-Sok Ha, Jun Nyung Lee, Tae Gyun Kwon, Dong-Hyung Cho, Jun-Koo Yi, Myoung Ok Kim, Zae Young Ryoo, Song Park
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Prostate cancer
Metastasis
mCRPC
ZNF507
TGF-β signal
Online Access:https://doi.org/10.1186/s13046-021-02094-3

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