Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B.
We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-t...
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2016-01-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4703342?pdf=render |
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doaj-6d4d45c6a517456d849b0991332dcde52020-11-25T02:08:39ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352016-01-01101e000430410.1371/journal.pntd.0004304Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B.Gloria MorizotRomain JouffroyAlbert FayePaul ChabertKatia BelhouariRuxandra CalinCaroline CharlierPatrick MiailhesJean-Yves SiriezOussama MouriHélène YeraJacques GilquinRoland TubianaFanny LanternierMarie-France MamzerChristophe LegendreDominique PeyramondEric CaumesOlivier LortholaryPierre BuffetWe report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure.http://europepmc.org/articles/PMC4703342?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gloria Morizot Romain Jouffroy Albert Faye Paul Chabert Katia Belhouari Ruxandra Calin Caroline Charlier Patrick Miailhes Jean-Yves Siriez Oussama Mouri Hélène Yera Jacques Gilquin Roland Tubiana Fanny Lanternier Marie-France Mamzer Christophe Legendre Dominique Peyramond Eric Caumes Olivier Lortholary Pierre Buffet |
spellingShingle |
Gloria Morizot Romain Jouffroy Albert Faye Paul Chabert Katia Belhouari Ruxandra Calin Caroline Charlier Patrick Miailhes Jean-Yves Siriez Oussama Mouri Hélène Yera Jacques Gilquin Roland Tubiana Fanny Lanternier Marie-France Mamzer Christophe Legendre Dominique Peyramond Eric Caumes Olivier Lortholary Pierre Buffet Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. PLoS Neglected Tropical Diseases |
author_facet |
Gloria Morizot Romain Jouffroy Albert Faye Paul Chabert Katia Belhouari Ruxandra Calin Caroline Charlier Patrick Miailhes Jean-Yves Siriez Oussama Mouri Hélène Yera Jacques Gilquin Roland Tubiana Fanny Lanternier Marie-France Mamzer Christophe Legendre Dominique Peyramond Eric Caumes Olivier Lortholary Pierre Buffet |
author_sort |
Gloria Morizot |
title |
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. |
title_short |
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. |
title_full |
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. |
title_fullStr |
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. |
title_full_unstemmed |
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B. |
title_sort |
antimony to cure visceral leishmaniasis unresponsive to liposomal amphotericin b. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS Neglected Tropical Diseases |
issn |
1935-2727 1935-2735 |
publishDate |
2016-01-01 |
description |
We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure. |
url |
http://europepmc.org/articles/PMC4703342?pdf=render |
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