Post-operative pain relief in children following caudal bupivacaine and buprenorphine--a comparative study.

• Main Authors: Anilkumar T, Karpurkar S, Shinde V
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 1994-04-01
• Series: Journal of Postgraduate Medicine
• Subjects: Analgesics; Opioid; pharmacology; therapeutic use; Anesthesia; Caudal; Anesthetics; Local; Bupivacaine; Buprenorphine; Child; Preschool; Comparative Study; Human; India; Infant; Pain; Postoperative; drug therapy
• Online Access: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1994;volume=40;issue=2;spage=61;epage=4;aulast=Anilkumar

Eighty-five paediatric patients (age range: 6 mths-12yrs) undergoing lower abdominal surgery were studied for post-operative pain relief following either caudal bupivacaine (GpI: n = 43) or buprenorphine (GpII: n = 42). Bupivacaine was administered as 0.5ml/kg body weight of 0.25% solution and buprenorphine as 4 micrograms/ml and volume of 0.5 ml/Kg body weight in normal saline. Post-operatively pain was graded on a 4-point scale and behaviour on a 5-point scale. Any post-operative complications and need for additional analgesia were also noted. Bupivacaine provided good pain relief in the early post-operative hours but buprenorphine provided pain relief lasting for 24 hrs or more post-operatively. Post-operative behaviour of 10 patients receiving buprenorphine was graded as cheerful as compared to 2 from bupivacaine group. Till the end of observation period (i.e. 8 hr post-operatively), majority of patients receiving buprenorphine remained cheerful.