A code within the genetic code: codon usage regulates co-translational protein folding

Abstract The genetic code is degenerate, and most amino acids are encoded by two to six synonymous codons. Codon usage bias, the preference for certain synonymous codons, is a universal feature of all genomes examined. Synonymous codon mutations were previously thought to be silent; however, a growi...

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Bibliographic Details
Main Author: Yi Liu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cell Communication and Signaling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12964-020-00642-6