Refolding Technologies for Antibody Fragments
Refolding is one of the production technologies for pharmaceutical grade antibody fragments. Detergents and denaturants are primarily used to solubilize the insoluble proteins. The solubilized and denatured proteins are refolded by reducing the concentration of the denaturants or detergents. Several...
Main Authors: | Tsutomu Arakawa, Daisuke Ejima |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-05-01
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Series: | Antibodies |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4468/3/2/232 |
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