Refolding Technologies for Antibody Fragments

Refolding Technologies for Antibody Fragments

Refolding is one of the production technologies for pharmaceutical grade antibody fragments. Detergents and denaturants are primarily used to solubilize the insoluble proteins. The solubilized and denatured proteins are refolded by reducing the concentration of the denaturants or detergents. Several...

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Bibliographic Details
Main Authors:	Tsutomu Arakawa, Daisuke Ejima
Format:	Article
Language:	English
Published:	MDPI AG 2014-05-01
Series:	Antibodies
Subjects:	refolding dialysis dilution C12-L-Glu antibody fragments
Online Access:	http://www.mdpi.com/2073-4468/3/2/232

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