Theft and Reception of Host Cell's Sialic Acid: Dynamics of Trypanosoma Cruzi Trans-sialidases and Mucin-Like Molecules on Chagas' Disease Immunomodulation

Theft and Reception of Host Cell's Sialic Acid: Dynamics of Trypanosoma Cruzi Trans-sialidases and Mucin-Like Molecules on Chagas' Disease Immunomodulation

The last decades have produced a plethora of evidence on the role of glycans, from cell adhesion to signaling pathways. Much of that information pertains to their role on the immune system and their importance on the surface of many human pathogens. A clear example of this is the flagellated protozo...

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Bibliographic Details
Main Authors: Leonardo Marques da Fonseca, Kelli Monteiro da Costa, Victoria de Sousa Chaves, Célio Geraldo Freire-de-Lima, Alexandre Morrot, Lucia Mendonça-Previato, Jose Osvaldo Previato, Leonardo Freire-de-Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
Trypanosoma cruzi
trans-sialidase
mucin-like molecule
sialic acid
glycan-binding protein
infectious disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00164/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00164/full

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