Mitochondrial Reactive Oxygen Species Are Essential for the Development of Psoriatic Inflammation

Mitochondrial Reactive Oxygen Species Are Essential for the Development of Psoriatic Inflammation

Psoriasis is a common immune-mediated, chronic, inflammatory skin disease that affects approximately 2–3% of the population worldwide. Although there is increasing evidence regarding the essential roles of the interleukin (IL)-23/IL-17 axis and dendritic cell (DC)-T cell crosstalk in the development...

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Bibliographic Details
Main Authors: Soichi Mizuguchi, Kazuhito Gotoh, Yuya Nakashima, Daiki Setoyama, Yurie Takata, Shouichi Ohga, Dongchon Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
C1qbp/p32
dendritic cells
mitochondrial ROS
IL-1β
psoriasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.714897/full

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