Short Link N promotes disc repair in a rabbit model of disc degeneration

Short Link N promotes disc repair in a rabbit model of disc degeneration

Abstract Background The degeneration of the intervertebral disc (IVD) is characterized by proteolytic degradation of the extracellular matrix, and its repair requires the production of an extracellular matrix with a high proteoglycan-to-collagen ratio characteristic of a nucleus pulposus (NP)-like p...

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Bibliographic Details
Main Authors: Fackson Mwale, Koichi Masuda, Michael P. Grant, Laura M. Epure, Kenji Kato, Shingo Miyazaki, Kevin Cheng, Junichi Yamada, Won C. Bae, Carol Muehleman, Peter J. Roughley, John Antoniou
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Arthritis Research & Therapy
Subjects:
Intervertebral disc degeneration
Regeneration
Tissue engineering
Collagen
Proteoglycans
Bioactive peptides
Online Access:http://link.springer.com/article/10.1186/s13075-018-1625-9

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