A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D<sub>2</sub>-like Receptors
Investigations on functional selectivity of GPCR ligands have become increasingly important to identify compounds with a potentially more beneficial side effect profile. In order to discriminate between individual signaling pathways, the determination of β-arrestin2 recruitment, in addition to G-pro...
Main Authors: | Lisa Forster, Lukas Grätz, Denise Mönnich, Günther Bernhardt, Steffen Pockes |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/17/6103 |
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