Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes

Objective. Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrea...

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Main Authors: Lima Lawrence, Oscar Tovar-Camargo, M. Cecilia Lansang, Vinni Makin
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2018/1723695
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spelling doaj-6da6fba155c544899109d4744e3273de2020-11-25T01:39:10ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2018-01-01201810.1155/2018/17236951723695Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding DiabetesLima Lawrence0Oscar Tovar-Camargo1M. Cecilia Lansang2Vinni Makin3Cleveland Clinic, Department of Endocrinology and Metabolism, Cleveland, OH, USACleveland Clinic, Department of Anesthesiology, Cleveland, OH, USACleveland Clinic, Department of Endocrinology and Metabolism, Cleveland, OH, USACleveland Clinic, Department of Endocrinology and Metabolism, Cleveland, OH, USAObjective. Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrease short- and long-term morbidity. Methods. Herein, we describe a case of a 41-year-old female with longstanding, uncontrolled type 2 diabetes, who presented with classical findings of diabetic myonecrosis. Results. Our patient underwent extensive laboratory and imaging studies prior to diagnosis due to its rarity and similarity in presentation with other commonly noted musculoskeletal conditions. We emphasize the clinical presentation, laboratory and imaging findings, treatment regimen, and prognosis associated with diabetic myonecrosis. Conclusion. Diabetic myonecrosis is a rare complication of longstanding, poorly controlled diabetes mellitus. The diagnosis requires a high index of suspicion in the right clinical setting: acute onset nontraumatic muscular pain with associated findings on clinical exam, laboratory studies, and imaging. While the short-term prognosis is good, the recurrence rate remains high and long-term prognosis is poor given underlying uncontrolled diabetes and associated sequelae.http://dx.doi.org/10.1155/2018/1723695
collection DOAJ
language English
format Article
sources DOAJ
author Lima Lawrence
Oscar Tovar-Camargo
M. Cecilia Lansang
Vinni Makin
spellingShingle Lima Lawrence
Oscar Tovar-Camargo
M. Cecilia Lansang
Vinni Makin
Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
Case Reports in Endocrinology
author_facet Lima Lawrence
Oscar Tovar-Camargo
M. Cecilia Lansang
Vinni Makin
author_sort Lima Lawrence
title Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
title_short Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
title_full Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
title_fullStr Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
title_full_unstemmed Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
title_sort diabetic myonecrosis: a diagnostic and treatment challenge in longstanding diabetes
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2018-01-01
description Objective. Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrease short- and long-term morbidity. Methods. Herein, we describe a case of a 41-year-old female with longstanding, uncontrolled type 2 diabetes, who presented with classical findings of diabetic myonecrosis. Results. Our patient underwent extensive laboratory and imaging studies prior to diagnosis due to its rarity and similarity in presentation with other commonly noted musculoskeletal conditions. We emphasize the clinical presentation, laboratory and imaging findings, treatment regimen, and prognosis associated with diabetic myonecrosis. Conclusion. Diabetic myonecrosis is a rare complication of longstanding, poorly controlled diabetes mellitus. The diagnosis requires a high index of suspicion in the right clinical setting: acute onset nontraumatic muscular pain with associated findings on clinical exam, laboratory studies, and imaging. While the short-term prognosis is good, the recurrence rate remains high and long-term prognosis is poor given underlying uncontrolled diabetes and associated sequelae.
url http://dx.doi.org/10.1155/2018/1723695
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AT oscartovarcamargo diabeticmyonecrosisadiagnosticandtreatmentchallengeinlongstandingdiabetes
AT mcecilialansang diabeticmyonecrosisadiagnosticandtreatmentchallengeinlongstandingdiabetes
AT vinnimakin diabeticmyonecrosisadiagnosticandtreatmentchallengeinlongstandingdiabetes
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