UPLC–MS/MS for the determination of azilsartan in beagle dog plasma and its application in a pharmacokinetics study
The purpose of the study is to develop an ultra performance liquid chromatography-tandem mass spectrometry (UPLC–MS/MS) to determinate the concentration of azilsartan in the dog plasma. After precipitated by methanol, the plasma sample containing azilsartan and diazepam (internal standard, IS) was d...
Main Authors: | Cheng Gong, Junfeng Wang, Yinghua Sun, Dawei Ding, Lu Zhong, Meng Zhu, Jin Sun, Xiangrong Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
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Series: | Asian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S181808761400097X |
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