Modern Approach in Premature Ovarian Failure
Premature ovarian failure (POF) is a condition affecting 1-2% of women younger than 40 years of age, characterized by amenorrhea, hypoestrogenism and elevated gonadotropin levels. In the last years it became a problem of social health interest as the frequency increased due to environmental factors...
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doaj-6db7628c43ea47749406f02c948f1af92021-09-05T14:01:23ZengSciendoRomanian Journal of Diabetes Nutrition and Metabolic Diseases2284-64172014-09-0121322923810.2478/rjdnmd-2014-0028rjdnmd-2014-0028Modern Approach in Premature Ovarian FailurePacu Irina0Ionescu Cringu1Serafinceanu Cristian2Pantea-Stoian Anca Mihaela3Elian Viviana4 Clinical Emergency Hospital “Sf. Pantelimon” Bucharest, Department of Obstetrics and Gynecology, University of Medicine “Carol Davila” Bucharest, Romania Clinical Emergency Hospital “Sf. Pantelimon” Bucharest, Department of Obstetrics and Gynecology, University of Medicine “Carol Davila” Bucharest, Romania “N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases Bucharest, University of Medicine “Carol Davila” Bucharest, Romania “N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases Bucharest, University of Medicine “Carol Davila” Bucharest, Romania “N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases Bucharest, University of Medicine “Carol Davila” Bucharest, RomaniaPremature ovarian failure (POF) is a condition affecting 1-2% of women younger than 40 years of age, characterized by amenorrhea, hypoestrogenism and elevated gonadotropin levels. In the last years it became a problem of social health interest as the frequency increased due to environmental factors and new, efficient methods for cancer treatment in young women. Few genes have beed identified to explain cases of POF but there are also autoimmune associated conditions and an increasing number of iatrogenic cases (chemotherapy, surgery, radiotherapy). Modern approach in POF means not only a precise etiological diagnosis, but also a correct counseling for these patients who often want to become parents, and a chance for a healthy life without the long term consequences of estrogen deprivation from an early age. In vitro fertilization (IVF) techniques can be useful for certain cases but research is needed on strategies to improve fertility for women who have follicles remaining in the ovaries.https://doi.org/10.2478/rjdnmd-2014-0028premature ovarian failureestrogen deprivationautoimmune etiologyinfertilityhormonal substitution |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pacu Irina Ionescu Cringu Serafinceanu Cristian Pantea-Stoian Anca Mihaela Elian Viviana |
spellingShingle |
Pacu Irina Ionescu Cringu Serafinceanu Cristian Pantea-Stoian Anca Mihaela Elian Viviana Modern Approach in Premature Ovarian Failure Romanian Journal of Diabetes Nutrition and Metabolic Diseases premature ovarian failure estrogen deprivation autoimmune etiology infertility hormonal substitution |
author_facet |
Pacu Irina Ionescu Cringu Serafinceanu Cristian Pantea-Stoian Anca Mihaela Elian Viviana |
author_sort |
Pacu Irina |
title |
Modern Approach in Premature Ovarian Failure |
title_short |
Modern Approach in Premature Ovarian Failure |
title_full |
Modern Approach in Premature Ovarian Failure |
title_fullStr |
Modern Approach in Premature Ovarian Failure |
title_full_unstemmed |
Modern Approach in Premature Ovarian Failure |
title_sort |
modern approach in premature ovarian failure |
publisher |
Sciendo |
series |
Romanian Journal of Diabetes Nutrition and Metabolic Diseases |
issn |
2284-6417 |
publishDate |
2014-09-01 |
description |
Premature ovarian failure (POF) is a condition affecting 1-2% of women younger than 40 years of age, characterized by amenorrhea, hypoestrogenism and elevated gonadotropin levels. In the last years it became a problem of social health interest as the frequency increased due to environmental factors and new, efficient methods for cancer treatment in young women. Few genes have beed identified to explain cases of POF but there are also autoimmune associated conditions and an increasing number of iatrogenic cases (chemotherapy, surgery, radiotherapy). Modern approach in POF means not only a precise etiological diagnosis, but also a correct counseling for these patients who often want to become parents, and a chance for a healthy life without the long term consequences of estrogen deprivation from an early age. In vitro fertilization (IVF) techniques can be useful for certain cases but research is needed on strategies to improve fertility for women who have follicles remaining in the ovaries. |
topic |
premature ovarian failure estrogen deprivation autoimmune etiology infertility hormonal substitution |
url |
https://doi.org/10.2478/rjdnmd-2014-0028 |
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