Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.

Bibliographic Details
Main Authors:	Gaoqian Feng, Bruce D. Wines, Liriye Kurtovic, Jo-Anne Chan, Philippe Boeuf, Vanessa Mollard, Anton Cozijnsen, Damien R. Drew, Rob J. Center, Daniel L. Marshall, Sandra Chishimba, Geoffrey I. McFadden, Arlene E. Dent, Kiprotich Chelimo, Michelle J. Boyle, James W. Kazura, P. Mark Hogarth, James G. Beeson
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-03-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-21998-4

id	doaj-6df085e64a2441099441e81ae6947fa5
record_format	Article
spelling	doaj-6df085e64a2441099441e81ae6947fa52021-03-21T12:15:00ZengNature Publishing GroupNature Communications2041-17232021-03-0112111610.1038/s41467-021-21998-4Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoitesGaoqian Feng0Bruce D. Wines1Liriye Kurtovic2Jo-Anne Chan3Philippe Boeuf4Vanessa Mollard5Anton Cozijnsen6Damien R. Drew7Rob J. Center8Daniel L. Marshall9Sandra Chishimba10Geoffrey I. McFadden11Arlene E. Dent12Kiprotich Chelimo13Michelle J. Boyle14James W. Kazura15P. Mark Hogarth16James G. Beeson17Burnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthSchool of BioSciences, The University of MelbourneSchool of BioSciences, The University of MelbourneBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthSchool of BioSciences, The University of MelbourneCentre for Global Health and Diseases, Case Western Reserve UniversityDepartment of Biomedical Science and Technology, Maseno UniversityBurnet Institute for Medical Research and Public HealthCentre for Global Health and Diseases, Case Western Reserve UniversityBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthAntibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.https://doi.org/10.1038/s41467-021-21998-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson
spellingShingle	Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites Nature Communications
author_facet	Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson
author_sort	Gaoqian Feng
title	Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_short	Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_full	Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_fullStr	Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_full_unstemmed	Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_sort	mechanisms and targets of fcγ-receptor mediated immunity to malaria sporozoites
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-03-01
description	Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.
url	https://doi.org/10.1038/s41467-021-21998-4
work_keys_str_mv	AT gaoqianfeng mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT brucedwines mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT liriyekurtovic mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT joannechan mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT philippeboeuf mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT vanessamollard mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT antoncozijnsen mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT damienrdrew mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT robjcenter mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT daniellmarshall mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT sandrachishimba mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT geoffreyimcfadden mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT arleneedent mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT kiprotichchelimo mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT michellejboyle mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT jameswkazura mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT pmarkhogarth mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites AT jamesgbeeson mechanismsandtargetsoffcgreceptormediatedimmunitytomalariasporozoites
_version_	1724210752736198656

Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

Similar Items