Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.
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2021-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-21998-4 |
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doaj-6df085e64a2441099441e81ae6947fa52021-03-21T12:15:00ZengNature Publishing GroupNature Communications2041-17232021-03-0112111610.1038/s41467-021-21998-4Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoitesGaoqian Feng0Bruce D. Wines1Liriye Kurtovic2Jo-Anne Chan3Philippe Boeuf4Vanessa Mollard5Anton Cozijnsen6Damien R. Drew7Rob J. Center8Daniel L. Marshall9Sandra Chishimba10Geoffrey I. McFadden11Arlene E. Dent12Kiprotich Chelimo13Michelle J. Boyle14James W. Kazura15P. Mark Hogarth16James G. Beeson17Burnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthSchool of BioSciences, The University of MelbourneSchool of BioSciences, The University of MelbourneBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthSchool of BioSciences, The University of MelbourneCentre for Global Health and Diseases, Case Western Reserve UniversityDepartment of Biomedical Science and Technology, Maseno UniversityBurnet Institute for Medical Research and Public HealthCentre for Global Health and Diseases, Case Western Reserve UniversityBurnet Institute for Medical Research and Public HealthBurnet Institute for Medical Research and Public HealthAntibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.https://doi.org/10.1038/s41467-021-21998-4 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson |
spellingShingle |
Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites Nature Communications |
author_facet |
Gaoqian Feng Bruce D. Wines Liriye Kurtovic Jo-Anne Chan Philippe Boeuf Vanessa Mollard Anton Cozijnsen Damien R. Drew Rob J. Center Daniel L. Marshall Sandra Chishimba Geoffrey I. McFadden Arlene E. Dent Kiprotich Chelimo Michelle J. Boyle James W. Kazura P. Mark Hogarth James G. Beeson |
author_sort |
Gaoqian Feng |
title |
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites |
title_short |
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites |
title_full |
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites |
title_fullStr |
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites |
title_full_unstemmed |
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites |
title_sort |
mechanisms and targets of fcγ-receptor mediated immunity to malaria sporozoites |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-03-01 |
description |
Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies. |
url |
https://doi.org/10.1038/s41467-021-21998-4 |
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