Ultrasonographic Evaluation of Thyroid Nodules with Pathologic Correlation
Introduction: Thyroid nodules are very common and can occur in upto 50% of the adult population. Ultrasonography is often the initial investigative modality used in the detection and characterisation of various thyroid nodules. Aim: To evaluate the diagnostic accuracy of ultrasonography in char...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Pvt. Ltd.
2017-04-01
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Series: | International Journal of Anatomy Radiology and Surgery |
Subjects: | |
Online Access: | http://www.ijars.net/articles/PDF/2266/23868_CE[VSU]_F(GH)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdf |
Summary: | Introduction: Thyroid nodules are very common and can
occur in upto 50% of the adult population. Ultrasonography
is often the initial investigative modality used in the
detection and characterisation of various thyroid nodules.
Aim: To evaluate the diagnostic accuracy of ultrasonography
in characterising benign and malignant thyroid nodules
by correlating the sonographic findings with pathological
diagnosis as reference.
Materials and Methods: In this prospective study, a total
of 138 thyroid nodules detected on ultrasonography were
further evaluated with Fine Needle Aspiration Cytology
(FNAC) and/or Histopathological Examination (HPE).
The sonographic features such as internal composition,
echotexture, shape, margins, presence or absence of
peripheral halo, calcification and internal vascularity were
correlated with the final diagnosis.
Results: The incidence of malignancy in this study was
10.1% (14/138). Malignant nodules tended to show solid
or predominantly solid composition (sensitivity 100%,
specificity 43.5%, accuracy 49.2%), hypoechoic pattern
(sensitivity 85.7%, specificity 67.7%, accuracy 69.5%),
taller-than-wider shape (sensitivity 64.2%, specificity
87%, accuracy 84.7%), irregular margins (sensitivity
78.5%, specificity 82.2%, accuracy 81.8%), calcifications
(sensitivity 78.5%, specificity 77.4%, accuracy 77.5%),
absence of peripheral halo (sensitivity 64.2%, specificity
53.2%, accuracy 54.3%) and internal vascularity (sensitivity
85.7%, specificity 64.5%, accuracy 66.6%).
Conclusion: Ultrasonography is a sensitive and specific
modality in the assessment of thyroid nodules with good
overall accuracy. The most useful sonographic feature that
helped to predict malignancy were a solid composition,
hypoechogenicity, taller-than-wider shape, irregular
margins and presence of calcification. |
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ISSN: | 2277-8543 2455-6874 |