Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men
Xiangli Xu,1 Fubo Zhou,2 Yang Hua,2 Beibei Liu,2 Lili Wang,2 Weihong Hou,2 Mingyu Xia2 1Department of Ultrasound, The Second Hospital of Harbin, Harbin, People’s Republic of China; 2Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of Chi...
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doaj-6e0d7e03055640ee8ee23c292b8831f52021-07-29T19:41:08ZengDove Medical PressInternational Journal of General Medicine1178-70742021-07-01Volume 143989399767357Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in MenXu XZhou FHua YLiu BWang LHou WXia MXiangli Xu,1 Fubo Zhou,2 Yang Hua,2 Beibei Liu,2 Lili Wang,2 Weihong Hou,2 Mingyu Xia2 1Department of Ultrasound, The Second Hospital of Harbin, Harbin, People’s Republic of China; 2Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Yang HuaDepartment of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Road, Beijing, 100053, People’s Republic of ChinaTel +86-10-83198923Fax +86-10-83198967Email dryanghua99@163.comObjective: To explore whether current smoking could influence plaque characteristics and determine its correlation to the irregular surface and calcification of carotid plaque.Methods: Three hundred and seventeen patients with severe carotid atherosclerosis stenosis (SCAS) detected by color duplex flow imaging (CDFI) and confirmed by CT angiography (CTA) were recruited. The results of laboratory parameters were collected by using electronic database of the hospital. Computerized tomography (CT) scanning and high-resolution ultrasonography were performed for assessment of plaque morphology, respectively.Results: All enrolled smokers and non-smokers had no significant difference among all characteristics not related to smoking. CT scanning could efficiently identify the difference among enrolled smokers and non-smokers not only for the characteristics related to smoking but also the onsets of carotid plaque. Surface morphology was also efficiently detected by ultrasonography. Further ridge trace analysis showed that ultrasonography is efficient for diagnosis of calcified plaque compared with gold standard for plaque diagnosis. Further correlation analysis showed that ultrasonography parameters could offer reliable evidence for plaque scores, which was associated with age index. Ultrasonography parameters could efficiently differentiate plaque morphologies among enrolled smokers and never-smokers.Conclusion: Current smoking was positively associated with plaque calcification onsets, and smoking cessation could efficiently attenuate such injury. High-frequency ultrasound can clearly distinguish the details of calcification with promising clinical significance for current smoking patients.Keywords: smoking, ultrasonography, carotid plaque, calcificationhttps://www.dovepress.com/current-smoking-is-a-risk-factor-for-the-irregular-surface-and-calcifi-peer-reviewed-fulltext-article-IJGMsmokingultrasonographycarotid plaquecalcification |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xu X Zhou F Hua Y Liu B Wang L Hou W Xia M |
spellingShingle |
Xu X Zhou F Hua Y Liu B Wang L Hou W Xia M Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men International Journal of General Medicine smoking ultrasonography carotid plaque calcification |
author_facet |
Xu X Zhou F Hua Y Liu B Wang L Hou W Xia M |
author_sort |
Xu X |
title |
Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men |
title_short |
Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men |
title_full |
Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men |
title_fullStr |
Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men |
title_full_unstemmed |
Current Smoking is a Risk Factor for the Irregular Surface and Calcification of Carotid Plaque in Men |
title_sort |
current smoking is a risk factor for the irregular surface and calcification of carotid plaque in men |
publisher |
Dove Medical Press |
series |
International Journal of General Medicine |
issn |
1178-7074 |
publishDate |
2021-07-01 |
description |
Xiangli Xu,1 Fubo Zhou,2 Yang Hua,2 Beibei Liu,2 Lili Wang,2 Weihong Hou,2 Mingyu Xia2 1Department of Ultrasound, The Second Hospital of Harbin, Harbin, People’s Republic of China; 2Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Yang HuaDepartment of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Road, Beijing, 100053, People’s Republic of ChinaTel +86-10-83198923Fax +86-10-83198967Email dryanghua99@163.comObjective: To explore whether current smoking could influence plaque characteristics and determine its correlation to the irregular surface and calcification of carotid plaque.Methods: Three hundred and seventeen patients with severe carotid atherosclerosis stenosis (SCAS) detected by color duplex flow imaging (CDFI) and confirmed by CT angiography (CTA) were recruited. The results of laboratory parameters were collected by using electronic database of the hospital. Computerized tomography (CT) scanning and high-resolution ultrasonography were performed for assessment of plaque morphology, respectively.Results: All enrolled smokers and non-smokers had no significant difference among all characteristics not related to smoking. CT scanning could efficiently identify the difference among enrolled smokers and non-smokers not only for the characteristics related to smoking but also the onsets of carotid plaque. Surface morphology was also efficiently detected by ultrasonography. Further ridge trace analysis showed that ultrasonography is efficient for diagnosis of calcified plaque compared with gold standard for plaque diagnosis. Further correlation analysis showed that ultrasonography parameters could offer reliable evidence for plaque scores, which was associated with age index. Ultrasonography parameters could efficiently differentiate plaque morphologies among enrolled smokers and never-smokers.Conclusion: Current smoking was positively associated with plaque calcification onsets, and smoking cessation could efficiently attenuate such injury. High-frequency ultrasound can clearly distinguish the details of calcification with promising clinical significance for current smoking patients.Keywords: smoking, ultrasonography, carotid plaque, calcification |
topic |
smoking ultrasonography carotid plaque calcification |
url |
https://www.dovepress.com/current-smoking-is-a-risk-factor-for-the-irregular-surface-and-calcifi-peer-reviewed-fulltext-article-IJGM |
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