Sterols affecting meiosis: novel chemical syntheses and the biological activity and spectral properties of the synthetic sterols

Sterols affecting meiosis: novel chemical syntheses and the biological activity and spectral properties of the synthetic sterols

4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol (I) from human follicular fluid and 4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol (II) from bull testes have been reported to activate meiosis in mouse oocytes (Byskov et al., 1995. Nature. 374: 559–562). Described herein are new chemical syntheses of I, II, a...

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Bibliographic Details
Main Authors: Benfang Ruan, Shinya Watanabe, John J. Eppig, Christopher Kwoh, Natasha Dzidic, Jihai Pang, William K. Wilson, George J. Schroepfer, Jr.
Format: Article
Language:English
Published: Elsevier 1998-10-01
Series:Journal of Lipid Research
Subjects:
mass spectrometry
nuclear magnetic resonance
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324998

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