Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and its prevalence increases continuously. Here, we reprogrammed fibroblasts of a high grade NAFLD patient with homozygous wildtype PNPLA3 genotype. We characterized the induced pluripotent stem cells (iP...
Main Authors: | Nina Graffmann, Martina Bohndorf, Audrey Ncube, Wasco Wruck, Karl Kashofer, Kurt Zatloukal, James Adjaye |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
|
Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S187350611830179X |
Similar Items
-
Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30–40% steatosis) with homozygous wildtype PNPLA3 genotype
by: Nina Graffmann, et al.
Published: (2018-08-01) -
Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density.
by: Nina Graffmann, et al.
Published: (2018-01-01) -
Fibroblast-derived integration-free iPSC line ISRM-NBS1 from an 18-year-old Nijmegen Breakage Syndrome patient carrying the homozygous NBN c.657_661del5 mutation
by: Soraia Martins, et al.
Published: (2019-01-01) -
Derivation and characterization of integration-free iPSC line ISRM-UM51 derived from SIX2-positive renal cells isolated from urine of an African male expressing the CYP2D6 *4/*17 variant which confers intermediate drug metabolizing activity
by: Martina Bohndorf, et al.
Published: (2017-12-01) -
Lymphoblast-derived integration-free iPSC line AD-TREM2-1 from a 67 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant
by: Soraia Martins, et al.
Published: (2018-05-01)