Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome

Abstract Objective Infantile spasm syndrome (ISS) is an epileptic encephalopathy without established treatment after the failure to standard of care based on steroids and vigabatrin. Converging lines of evidence indicating a role of NR2B subunits of the N‐methyl‐D‐aspartate (NMDA) receptor on the on...

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Bibliographic Details
Main Authors: Stéphane Auvin, Blandine Dozières‐Puyravel, Andreja Avbersek, David Sciberras, Jo Collier, Karine Leclercq, Pavel Mares, Rafal M. Kaminski, Pierandrea Muglia
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50998

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https://doi.org/10.1002/acn3.50998

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