Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group
Novel N-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction of N-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA deri...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2004-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2004/732420 |
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doaj-6e2e6a725afd44f4aace70bfb51bbe152020-11-25T01:04:42ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102004-01-0112939810.1155/2004/732420Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy GroupH. S. Patel0H. D. Desai1H. J. Mistry2Department of Chemistry, S.P. UniversityV.V. Nagar -388 120, Gujarat, IndiaDepartment of Chemistry, S.P. UniversityV.V. Nagar -388 120, Gujarat, IndiaDepartment of Chemistry, S.P. UniversityV.V. Nagar -388 120, Gujarat, IndiaNovel N-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction of N-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA derivatives are then reacted with chloro acetyl chloride to give corresponding (N-Chloroacetyl) derivatives (3a-h). These derivatives are then reacted with N-phenyl piperazine to yield the corresponding piperazine derivatives (4a-h).http://dx.doi.org/10.1155/2004/732420 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
H. S. Patel H. D. Desai H. J. Mistry |
| spellingShingle |
H. S. Patel H. D. Desai H. J. Mistry Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group E-Journal of Chemistry |
| author_facet |
H. S. Patel H. D. Desai H. J. Mistry |
| author_sort |
H. S. Patel |
| title |
Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group |
| title_short |
Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group |
| title_full |
Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group |
| title_fullStr |
Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group |
| title_full_unstemmed |
Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group |
| title_sort |
synthesis and antimicrobial activity of some new piperazine derivaties containing aryl sulfonyloxy group |
| publisher |
Hindawi Limited |
| series |
E-Journal of Chemistry |
| issn |
0973-4945 2090-9810 |
| publishDate |
2004-01-01 |
| description |
Novel N-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction of N-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA derivatives are then reacted with chloro acetyl chloride to give corresponding (N-Chloroacetyl) derivatives (3a-h). These derivatives are then reacted with N-phenyl piperazine to yield the corresponding piperazine derivatives (4a-h). |
| url |
http://dx.doi.org/10.1155/2004/732420 |
| work_keys_str_mv |
AT hspatel synthesisandantimicrobialactivityofsomenewpiperazinederivatiescontainingarylsulfonyloxygroup AT hddesai synthesisandantimicrobialactivityofsomenewpiperazinederivatiescontainingarylsulfonyloxygroup AT hjmistry synthesisandantimicrobialactivityofsomenewpiperazinederivatiescontainingarylsulfonyloxygroup |
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