Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.

Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.

Human amniotic epithelial cells (hAEC) have stem cell-like features and immunomodulatory properties. Here we show that hAEC significantly suppressed splenocyte proliferation in vitro and potently attenuated a mouse model of multiple sclerosis (MS). Central nervous system (CNS) CD3(+) T cell and F4/8...

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Bibliographic Details
Main Authors: Yu Han Liu, Vijesh Vaghjiani, Jing Yang Tee, Kelly To, Peng Cui, Ding Yuan Oh, Ursula Manuelpillai, Ban-Hock Toh, James Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22563398/pdf/?tool=EBI

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