Sample composition alters associations between age and brain structure

The influence of sample composition on human neuroimaging results is unknown. Here, the authors weight a large, community-based sample to better reflect the US population and describe how applying these sample weights changes conclusions about age-related variation in brain structure.

Bibliographic Details
Main Authors: Kaja Z. LeWinn, Margaret A. Sheridan, Katherine M. Keyes, Ava Hamilton, Katie A. McLaughlin
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00908-7
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spelling doaj-6e3b307c844442d2bf16453c5231bdda2021-05-11T07:16:14ZengNature Publishing GroupNature Communications2041-17232017-10-018111410.1038/s41467-017-00908-7Sample composition alters associations between age and brain structureKaja Z. LeWinn0Margaret A. Sheridan1Katherine M. Keyes2Ava Hamilton3Katie A. McLaughlin4Department of Psychiatry, University of CaliforniaClinical Psychology Department, University of North Carolina at Chapel HillDepartment of Epidemiology, Columbia UniversityDepartment of Epidemiology, Columbia UniversityDepartment of Psychology, University of WashingtonThe influence of sample composition on human neuroimaging results is unknown. Here, the authors weight a large, community-based sample to better reflect the US population and describe how applying these sample weights changes conclusions about age-related variation in brain structure.https://doi.org/10.1038/s41467-017-00908-7
collection DOAJ
language English
format Article
sources DOAJ
author Kaja Z. LeWinn
Margaret A. Sheridan
Katherine M. Keyes
Ava Hamilton
Katie A. McLaughlin
spellingShingle Kaja Z. LeWinn
Margaret A. Sheridan
Katherine M. Keyes
Ava Hamilton
Katie A. McLaughlin
Sample composition alters associations between age and brain structure
Nature Communications
author_facet Kaja Z. LeWinn
Margaret A. Sheridan
Katherine M. Keyes
Ava Hamilton
Katie A. McLaughlin
author_sort Kaja Z. LeWinn
title Sample composition alters associations between age and brain structure
title_short Sample composition alters associations between age and brain structure
title_full Sample composition alters associations between age and brain structure
title_fullStr Sample composition alters associations between age and brain structure
title_full_unstemmed Sample composition alters associations between age and brain structure
title_sort sample composition alters associations between age and brain structure
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-10-01
description The influence of sample composition on human neuroimaging results is unknown. Here, the authors weight a large, community-based sample to better reflect the US population and describe how applying these sample weights changes conclusions about age-related variation in brain structure.
url https://doi.org/10.1038/s41467-017-00908-7
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AT avahamilton samplecompositionaltersassociationsbetweenageandbrainstructure
AT katieamclaughlin samplecompositionaltersassociationsbetweenageandbrainstructure
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