Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma

Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma

Rhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common sarcoma of childhood. Despite multidrug chemotherapy regimens, surgical intervention, and radiation treatment, outcomes remain poor, especially in advanced disease, and novel therapies are needed for the treatment of these...

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Bibliographic Details
Main Authors: Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Gregory K. Friedman, Jennifer M. Coleman, James M. Markert, G. Yancey Gillespie, Elizabeth A. Beierle
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316300973

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http://www.sciencedirect.com/science/article/pii/S1936523316300973

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