Toxicity of Necrostatin-1 in Parkinson’s Disease Models

Toxicity of Necrostatin-1 in Parkinson’s Disease Models

Parkinson’s disease (PD) is a neurodegenerative disorder that is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. This neuronal loss, inherent to age, is related to exposure to environmental toxins and/or a genetic predisposition. PD-induced cell death has bee...

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Bibliographic Details
Main Authors: Eva Alegre-Cortés, Alicia Muriel-González, Saray Canales-Cortés, Elisabet Uribe-Carretero, Guadalupe Martínez-Chacón, Ana Aiastui, Adolfo López de Munain, Mireia Niso-Santano, Rosa A. Gonzalez-Polo, José M. Fuentes, Sokhna M.S Yakhine-Diop
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antioxidants
Subjects:
mitochondria
mitophagy
MLKL
necroptosis
RIP
rotenone
Online Access:https://www.mdpi.com/2076-3921/9/6/524

Internet

https://www.mdpi.com/2076-3921/9/6/524

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