Direct One-Pot Synthesis of Primary 4-Amino-2,3-diaryl-quinolines via Suzuki-Miyaura Cross-Coupling of 2-Aryl-4-azido-3-iodoquinolines with Arylboronic Acids

Palladium-catalyzed Suzuki-Miyaura cross-coupling of 2-aryl-4-azido-3-iodo-quinolines with arylboronic acids afforded the corresponding primary 4-amino-2,3-diarylquinolines in a single-pot operation along with symmetrical biaryls and traces of the 2,3-diaryl-4-azidoquinolines. A plausible mechanism,...

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Bibliographic Details
Main Authors: Mamasegare Mabel Mphahlele, Malose Jack Mphahlele
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/11/8958/

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