Unwanted Intra-operative Penile Erection During Pediatric Hypospadiasis Repair Comparison of Propofol and Halothane

• Main Authors: Hamid Reza Abbasi, Seyed Soheil Ben Razavi, Mohammad Reza Hajiesmaeili, Shekoufeh Behdad, Mohammad Mehdi Ghiamat, Ahmad Eghbali
• Format: Article
• Language: English
• Published: Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences 2013-09-01
• Series: Urology Journal
• Subjects: anesthesia; propofol; halothane; child; penile erection
• Online Access: http://www.urologyjournal.org/index.php/uj/article/view/1319/753
• ISSN: 1735-1308; 1735-546X

Purpose: To compare the erectile effect of propofol and halothane on unwanted intraoperativepenile erection (UIOPE) during pediatric hypospadiasis repair.Materials and Methods: One hundred and seventeen boys who were in the age range of6 months to 6 years and referred for hypospadiasis repair to our referral teaching hospitalwere included in this randomized clinical trial. Patients were randomly assigned to oneof the two study groups before anesthesia induction. Anesthesia was maintained with acontinuous intravenous infusion of propofol and inhalational halothane in the propofol (P)and halothane (H) groups, respectively. Data regarding the patients’ age, weight, pre- andintra-operative chordee, UIOPE, anesthesia time, surgery time, hematoma formation, andwound infection were collected. The Chi-Square and Fisher’s exact tests were used forcomparison.Results: No statistically significant differences were noted regarding age, weight, and preandintra-operative chordee between the two groups. The incidence of UIOPE (10.34%versus 57.63%; P = .000), anesthesia time (174.15 ± 15.02 versus 181.26 ± 15.19; P =.012), and surgery time (162.34 ± 12.99 versus 167.69 ± 13.90; P = .034) were significantlylower in group P compared with group H.Conclusion: The use of propofol during hypospadiasis surgical repair is more safe andeffective than halothane in preventing UIOPE and reducing surgery and anesthesia time.