Chemical Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiae

Chemical Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiae

Current approaches for identifying synergistic targets use cell culture models to see if the combined effect of clinically available drugs is better than predicted by their individual efficacy. New techniques are needed to systematically and rationally identify targets and pathways that may be syne...

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Bibliographic Details
Main Authors:	Joseph I. Kliegman, Dorothea Fiedler, Colm J. Ryan, Yi-Fan Xu, Xiao-yang Su, David Thomas, Max C. Caccese, Ada Cheng, Michael Shales, Joshua D. Rabinowitz, Nevan J. Krogan, Kevan M. Shokat
Format:	Article
Language:	English
Published:	Elsevier 2013-12-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124713007249

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