Genetic determinants of daytime napping and effects on cardiometabolic health
The genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations.
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20585-3 |
id |
doaj-6ea11ee769b14bf6a723c6ea903c4958 |
---|---|
record_format |
Article |
spelling |
doaj-6ea11ee769b14bf6a723c6ea903c49582021-02-14T12:13:14ZengNature Publishing GroupNature Communications2041-17232021-02-0112111510.1038/s41467-020-20585-3Genetic determinants of daytime napping and effects on cardiometabolic healthHassan S. Dashti0Iyas Daghlas1Jacqueline M. Lane2Yunru Huang3Miriam S. Udler4Heming Wang5Hanna M. Ollila6Samuel E. Jones7Jaegil Kim8Andrew R. Wood923andMe Research TeamMichael N. Weedon10Stella Aslibekyan11Marta Garaulet12Richa Saxena13Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School23andMe, Inc.Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolBroad InstituteCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolInstitute for Molecular Medicine FIMM, HiLIFE, University of HelsinkiGlaxoSmithKlineGenetics of Complex Traits, University of Exeter Medical SchoolGenetics of Complex Traits, University of Exeter Medical School23andMe, Inc.Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolThe genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations.https://doi.org/10.1038/s41467-020-20585-3 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hassan S. Dashti Iyas Daghlas Jacqueline M. Lane Yunru Huang Miriam S. Udler Heming Wang Hanna M. Ollila Samuel E. Jones Jaegil Kim Andrew R. Wood 23andMe Research Team Michael N. Weedon Stella Aslibekyan Marta Garaulet Richa Saxena |
spellingShingle |
Hassan S. Dashti Iyas Daghlas Jacqueline M. Lane Yunru Huang Miriam S. Udler Heming Wang Hanna M. Ollila Samuel E. Jones Jaegil Kim Andrew R. Wood 23andMe Research Team Michael N. Weedon Stella Aslibekyan Marta Garaulet Richa Saxena Genetic determinants of daytime napping and effects on cardiometabolic health Nature Communications |
author_facet |
Hassan S. Dashti Iyas Daghlas Jacqueline M. Lane Yunru Huang Miriam S. Udler Heming Wang Hanna M. Ollila Samuel E. Jones Jaegil Kim Andrew R. Wood 23andMe Research Team Michael N. Weedon Stella Aslibekyan Marta Garaulet Richa Saxena |
author_sort |
Hassan S. Dashti |
title |
Genetic determinants of daytime napping and effects on cardiometabolic health |
title_short |
Genetic determinants of daytime napping and effects on cardiometabolic health |
title_full |
Genetic determinants of daytime napping and effects on cardiometabolic health |
title_fullStr |
Genetic determinants of daytime napping and effects on cardiometabolic health |
title_full_unstemmed |
Genetic determinants of daytime napping and effects on cardiometabolic health |
title_sort |
genetic determinants of daytime napping and effects on cardiometabolic health |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-02-01 |
description |
The genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations. |
url |
https://doi.org/10.1038/s41467-020-20585-3 |
work_keys_str_mv |
AT hassansdashti geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT iyasdaghlas geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT jacquelinemlane geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT yunruhuang geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT miriamsudler geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT hemingwang geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT hannamollila geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT samuelejones geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT jaegilkim geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT andrewrwood geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT 23andmeresearchteam geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT michaelnweedon geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT stellaaslibekyan geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT martagaraulet geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth AT richasaxena geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth |
_version_ |
1724270878555897856 |