Genetic determinants of daytime napping and effects on cardiometabolic health

The genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations.

Bibliographic Details
Main Authors: Hassan S. Dashti, Iyas Daghlas, Jacqueline M. Lane, Yunru Huang, Miriam S. Udler, Heming Wang, Hanna M. Ollila, Samuel E. Jones, Jaegil Kim, Andrew R. Wood, 23andMe Research Team, Michael N. Weedon, Stella Aslibekyan, Marta Garaulet, Richa Saxena
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20585-3
id doaj-6ea11ee769b14bf6a723c6ea903c4958
record_format Article
spelling doaj-6ea11ee769b14bf6a723c6ea903c49582021-02-14T12:13:14ZengNature Publishing GroupNature Communications2041-17232021-02-0112111510.1038/s41467-020-20585-3Genetic determinants of daytime napping and effects on cardiometabolic healthHassan S. Dashti0Iyas Daghlas1Jacqueline M. Lane2Yunru Huang3Miriam S. Udler4Heming Wang5Hanna M. Ollila6Samuel E. Jones7Jaegil Kim8Andrew R. Wood923andMe Research TeamMichael N. Weedon10Stella Aslibekyan11Marta Garaulet12Richa Saxena13Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School23andMe, Inc.Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolBroad InstituteCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolInstitute for Molecular Medicine FIMM, HiLIFE, University of HelsinkiGlaxoSmithKlineGenetics of Complex Traits, University of Exeter Medical SchoolGenetics of Complex Traits, University of Exeter Medical School23andMe, Inc.Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital and Harvard Medical SchoolCenter for Genomic Medicine, Massachusetts General Hospital and Harvard Medical SchoolThe genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations.https://doi.org/10.1038/s41467-020-20585-3
collection DOAJ
language English
format Article
sources DOAJ
author Hassan S. Dashti
Iyas Daghlas
Jacqueline M. Lane
Yunru Huang
Miriam S. Udler
Heming Wang
Hanna M. Ollila
Samuel E. Jones
Jaegil Kim
Andrew R. Wood
23andMe Research Team
Michael N. Weedon
Stella Aslibekyan
Marta Garaulet
Richa Saxena
spellingShingle Hassan S. Dashti
Iyas Daghlas
Jacqueline M. Lane
Yunru Huang
Miriam S. Udler
Heming Wang
Hanna M. Ollila
Samuel E. Jones
Jaegil Kim
Andrew R. Wood
23andMe Research Team
Michael N. Weedon
Stella Aslibekyan
Marta Garaulet
Richa Saxena
Genetic determinants of daytime napping and effects on cardiometabolic health
Nature Communications
author_facet Hassan S. Dashti
Iyas Daghlas
Jacqueline M. Lane
Yunru Huang
Miriam S. Udler
Heming Wang
Hanna M. Ollila
Samuel E. Jones
Jaegil Kim
Andrew R. Wood
23andMe Research Team
Michael N. Weedon
Stella Aslibekyan
Marta Garaulet
Richa Saxena
author_sort Hassan S. Dashti
title Genetic determinants of daytime napping and effects on cardiometabolic health
title_short Genetic determinants of daytime napping and effects on cardiometabolic health
title_full Genetic determinants of daytime napping and effects on cardiometabolic health
title_fullStr Genetic determinants of daytime napping and effects on cardiometabolic health
title_full_unstemmed Genetic determinants of daytime napping and effects on cardiometabolic health
title_sort genetic determinants of daytime napping and effects on cardiometabolic health
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-02-01
description The genetic basis of daytime napping and the directional effect of daytime napping on cardiometabolic health are unknown. Here, the authors perform a genome-wide association study on self-reported daytime napping in the UK Biobank and Mendelian randomization to explore causal associations.
url https://doi.org/10.1038/s41467-020-20585-3
work_keys_str_mv AT hassansdashti geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT iyasdaghlas geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT jacquelinemlane geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT yunruhuang geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT miriamsudler geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT hemingwang geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT hannamollila geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT samuelejones geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT jaegilkim geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT andrewrwood geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT 23andmeresearchteam geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT michaelnweedon geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT stellaaslibekyan geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT martagaraulet geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
AT richasaxena geneticdeterminantsofdaytimenappingandeffectsoncardiometabolichealth
_version_ 1724270878555897856