Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment
Development of colorectal cancer has been considered as a result of imbalance of pro- and anti-inflammatory intestinal microenvironment accompanied by macrophage recruitment. Despite macrophages are implicated in remodeling tumor microenvironment, the mechanism of macrophage recruitment is not fully...
Main Authors: | Kejian Zou, Yaodong Wang, Yan Hu, Liansheng Zheng, Wanfu Xu, Guoxin Li |
---|---|
Format: | Article |
Language: | English |
Published: |
IOS Press
2017-03-01
|
Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317695962 |
Similar Items
-
The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer
by: Marjorie De la Fuente López, et al.
Published: (2018-11-01) -
Roles of CCL2-CCR2 Axis in the Tumor Microenvironment
by: Suguru Kadomoto, et al.
Published: (2021-08-01) -
CCL2: An Important Mediator Between Tumor Cells and Host Cells in Tumor Microenvironment
by: Jiakang Jin, et al.
Published: (2021-07-01) -
The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment
by: Kosuke Mizutani, et al.
Published: (2009-11-01) -
CCL18 IN COLORECTAL CANCER: AN EMERGING PRO-INVASIVE AND IMMUNOSUPPRESSIVE CHEMOKINE IN THE TUMOR MICROENVIRONMENT
by: Ana Manuela Canha Borges
Published: (2021)