In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis.

In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis.

BACKGROUND: Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania (Leishmania) amazonensis, an agent of simple and diffu...

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Bibliographic Details
Main Authors: Carolina de Siqueira Paladi, Isabella Aparecida Salerno Pimentel, Simone Katz, Rodrigo L O R Cunha, Wagner Alves de Souza Judice, Antonio C F Caires, Clara Lúcia Barbiéri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3352823?pdf=render

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