EXPERIENCE OF USING METHOTREXATE IN A PATIENT WITH EARLY OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

EXPERIENCE OF USING METHOTREXATE IN A PATIENT WITH EARLY OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

The article describes a case with a severe course of oligoarticular juvenile idiopathic arthritis with the development of contracture and destructive articular alterations. The successful use of methotrexate (15mg/m2 of body surface per week, subcutaneously) in a child with early arthritis (disease...

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Bibliographic Details
Main Authors: T. V. Sleptsova, E. I. Alexeeva, T. M. Bzarova, K. B. Isaeva, E. V. Mitenko
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2013-04-01
Series:Pediatričeskaâ Farmakologiâ
Subjects:
children
juvenile idiopathic arthritis
methotrexate
subcutaneous introduction
Online Access:https://www.pedpharma.ru/jour/article/view/244
Description
Summary:The article describes a case with a severe course of oligoarticular juvenile idiopathic arthritis with the development of contracture and destructive articular alterations. The successful use of methotrexate (15mg/m2 of body surface per week, subcutaneously) in a child with early arthritis (disease duration – less than 2 years) is described: 6 months after the therapy had started, acute inflammatory articular alterations, arthralgiae, morning stiffness terminated; in 12 months the range of motions in the affected joints recovered completely. The inactive disease phase and remission were registered in 6 and 12 months, accordingly. The remission has continued for 12 months.
ISSN:1727-5776
2500-3089

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