Defective Sphingolipids Metabolism and Tumor Associated Macrophages as the Possible Links Between Gaucher Disease and Blood Cancer Development

Defective Sphingolipids Metabolism and Tumor Associated Macrophages as the Possible Links Between Gaucher Disease and Blood Cancer Development

There is a rising number of evidence indicating the increased risk of cancer development in association with congenital metabolic errors. Although these diseases represent disorders of individual genes, they lead to the disruption of metabolic pathways resulting in metabolite accumulation or their d...

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Bibliographic Details
Main Authors: Marzena Wątek, Ewelina Piktel, Tomasz Wollny, Bonita Durnaś, Krzysztof Fiedoruk, Ewa Lech-Marańda, Robert Bucki
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
Gaucher disease
sphingolipids
cancer
tumor-associated macrophage
multiple myeloma
Online Access:https://www.mdpi.com/1422-0067/20/4/843

Internet

https://www.mdpi.com/1422-0067/20/4/843

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