Condition peroxidations and antioxidative systems with children at the influenza a h1n1 pdm09

• Main Author: N. A. Miromanova
• Format: Article
• Language: Russian
• Published: Journal Infectology 2014-09-01
• Series: Žurnal Infektologii
• Subjects: influenza; pneumonia; children; antioxidative systems; lipids peroxidation
• Online Access: https://journal.niidi.ru/jofin/article/view/217

The objective: to study a role peroxidation of lipids and antioxidative system at children at influenza А H1N1pdm09.Materials and methods: research prooxidatic and antioxidatic activity of blood at 114 children with an uncomplicated current of influenza A H1N1pdm09 and at 87 children with a pneumonia associated with a virus of influenza A H1N1pdm09 is carried out.Results of research: it is established, that uncomplicated forms of influenza A H1N1pdm09 at children’s age are accompanied by depression of antioxidatic protection and appreciable intensifying of processes peroxidations of lipids, depending on gravity of a clinical current of an infection. At the complicated current of influenza A H1N1pdm09 a pneumonia processes peroxidations of lipids proceed more intensively, especially at a serious current of pathological process.Conclusion: development of oxidising stress with prevalence of oxidizers is one of key pathogenetic links of formation of the serious and complicated forms of influenza A H1N1pdm09 at children.