Multiparametric biophysical profiling of red blood cells in malaria infection

Deshmukh et al. combine microscale magnetic levitation with minute density and magnetic susceptibility differences to enhance biophysical separation of cells. They demonstrate the feasibility of this approach on cells infected with malaria parasites, which simultaneously decrease host cell density a...

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Main Authors:	Shreya S. Deshmukh, Bikash Shakya, Anna Chen, Naside Gozde Durmus, Bryan Greenhouse, Elizabeth S. Egan, Utkan Demirci
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-021-02181-3

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spelling	doaj-6f106f1c607b4b18bd015bc9ab73be682021-06-13T11:33:40ZengNature Publishing GroupCommunications Biology2399-36422021-06-014111310.1038/s42003-021-02181-3Multiparametric biophysical profiling of red blood cells in malaria infectionShreya S. Deshmukh0Bikash Shakya1Anna Chen2Naside Gozde Durmus3Bryan Greenhouse4Elizabeth S. Egan5Utkan Demirci6Department of Bioengineering, Stanford University Schools of Engineering and MedicineDepartment of Pediatrics; Department of Microbiology and Immunology, Stanford University School of MedicineDepartment of Medicine, University of California San FranciscoDepartment of Radiology, Stanford University School of MedicineDepartment of Medicine, University of California San FranciscoDepartment of Pediatrics; Department of Microbiology and Immunology, Stanford University School of MedicineCanary Center for Early Cancer Detection, Department of Radiology, Stanford University School of MedicineDeshmukh et al. combine microscale magnetic levitation with minute density and magnetic susceptibility differences to enhance biophysical separation of cells. They demonstrate the feasibility of this approach on cells infected with malaria parasites, which simultaneously decrease host cell density and increase its magnetic susceptibility.https://doi.org/10.1038/s42003-021-02181-3
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shreya S. Deshmukh Bikash Shakya Anna Chen Naside Gozde Durmus Bryan Greenhouse Elizabeth S. Egan Utkan Demirci
spellingShingle	Shreya S. Deshmukh Bikash Shakya Anna Chen Naside Gozde Durmus Bryan Greenhouse Elizabeth S. Egan Utkan Demirci Multiparametric biophysical profiling of red blood cells in malaria infection Communications Biology
author_facet	Shreya S. Deshmukh Bikash Shakya Anna Chen Naside Gozde Durmus Bryan Greenhouse Elizabeth S. Egan Utkan Demirci
author_sort	Shreya S. Deshmukh
title	Multiparametric biophysical profiling of red blood cells in malaria infection
title_short	Multiparametric biophysical profiling of red blood cells in malaria infection
title_full	Multiparametric biophysical profiling of red blood cells in malaria infection
title_fullStr	Multiparametric biophysical profiling of red blood cells in malaria infection
title_full_unstemmed	Multiparametric biophysical profiling of red blood cells in malaria infection
title_sort	multiparametric biophysical profiling of red blood cells in malaria infection
publisher	Nature Publishing Group
series	Communications Biology
issn	2399-3642
publishDate	2021-06-01
description	Deshmukh et al. combine microscale magnetic levitation with minute density and magnetic susceptibility differences to enhance biophysical separation of cells. They demonstrate the feasibility of this approach on cells infected with malaria parasites, which simultaneously decrease host cell density and increase its magnetic susceptibility.
url	https://doi.org/10.1038/s42003-021-02181-3
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Multiparametric biophysical profiling of red blood cells in malaria infection

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