Clinical Development of c-MET Inhibition in Hepatocellular Carcinoma

Clinical Development of c-MET Inhibition in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death. In patients with advanced or unresectable HCC, there are few treatment options. Conventional chemotherapy has limited benefits. Sorafenib, a multi-kinase inhibitor, improves survival, but options for patients intolerant of...

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Bibliographic Details
Main Authors:	Joycelyn J. X. Lee, Jack J. Chan, Su Pin Choo
Format:	Article
Language:	English
Published:	MDPI AG 2015-10-01
Series:	Diseases
Subjects:	hepatocellular carcinoma (HCC) c-MET hepatocyte growth factor (HGF) c-MET inhibitor tivantinib cabozantinib
Online Access:	http://www.mdpi.com/2079-9721/3/4/306

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