COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES
Reaction of tin tetrachloride in a 2-propanol solution and 2-(7-bromo-2-oxo-5-phenyl-3H- 1,4-benzodiazepin-1-yl)acetohydrazide (“gidazepam”, hydazepam – HHy) made it possible to obtain for the first time the corresponding tin coordination compound [Sn(HHy)Cl4] (I). A synthetic technique of the templ...
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Odessa I. I. Mechnikov National University
2017-09-01
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doaj-6f331455e9bd47fe9abe5054ced887cd2020-11-24T23:08:04ZengOdessa I. I. Mechnikov National University Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ2304-09472414-59632017-09-01223(63)61510.18524/2304-0947.2017.3(63).109384109384COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDESI. I. Seifullina0G. V. Yalovskiy1I. M. Rakipov2V. I. Pavlovsky3Одеський національний університет імені І.І. Мечникова, кафедра загальної хімії та полімерівОдеський національний університет імені І.І. Мечникова, кафедра загальної хімії та полімерівОдеський національний політехнічний університет, хіміко-технологічний факультетФізико-хімічний інститут імені О.В. Богатського НАН УкраїниReaction of tin tetrachloride in a 2-propanol solution and 2-(7-bromo-2-oxo-5-phenyl-3H- 1,4-benzodiazepin-1-yl)acetohydrazide (“gidazepam”, hydazepam – HHy) made it possible to obtain for the first time the corresponding tin coordination compound [Sn(HHy)Cl4] (I). A synthetic technique of the template synthesis has been developed and a novel coordination compounds [Sn(HHySl)Cl3] (II), [Sn(HHySlNO2)Cl3] (III), [Sn(HHy2Nf)Cl3] (IV), [Sn(HHy2NfBr)Cl3] (V) in the systems HHy–(HSl, HSlNO2, H2Nf, H2NfBr)–SnCl4–2-propanol, where HSl is 2-hydroxybenz-, HSlNO2 – 2-hydroxy-5-nitrobenz-, H2Nf – 1-hydroxy- 2-naphth-, H2NfBr – 4-bromo-1-hydroxy-2-naphth-aldehydes, have been synthesized. They are crystalline substances readily soluble in DMF and acetonitrile and moderately soluble in ethanol. The composition and structure of the complexes were confirmed by a number of physicochemical methods: elemental analysis, electrical conductivity, mass spectrometry, IR spectroscopy and thermogravimetry. The measurement of the electrical conductivity of solutions of the I−V in DMF has shown that they all are non-electrolytes. It was found by the thermogravimetric method that the thermolysis of complexes I−V proceeds uniformly and is stepwise in nature. The presence of peaks of molecular ions of the corresponding hydrazones in the mass spectra of complexes II−V obtained by template synthesis confirmed the formation of these hydrazones and the participation in coordination to the Sn4+ ion in the reaction course. Tin(IV) coordination polyhedron in all complexes is the octahedron formed by: four chlorine atoms, the nitrogen atom of the hydrazide amino group and the oxygen atom of the ligand carbonyl group in I; three chlorine atoms, azomethine nitrogen atom and two oxygen atoms of the carbonyl and deprotonated hydroxy group of the ligand in II−V.http://heraldchem.onu.edu.ua/article/view/109384тетрахлорид стануму, гідазепам, гідразони, координаційні сполуки, темплатний синтез |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
I. I. Seifullina G. V. Yalovskiy I. M. Rakipov V. I. Pavlovsky |
spellingShingle |
I. I. Seifullina G. V. Yalovskiy I. M. Rakipov V. I. Pavlovsky COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ тетрахлорид стануму, гідазепам, гідразони, координаційні сполуки, темплатний синтез |
author_facet |
I. I. Seifullina G. V. Yalovskiy I. M. Rakipov V. I. Pavlovsky |
author_sort |
I. I. Seifullina |
title |
COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES |
title_short |
COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES |
title_full |
COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES |
title_fullStr |
COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES |
title_full_unstemmed |
COORDINATION COMPOUNDS OF TIN(IV) WITH HYDAZEPAM AND PRODUCTS OF ITS CONDENSATION WITH ARYLALDEHYDES |
title_sort |
coordination compounds of tin(iv) with hydazepam and products of its condensation with arylaldehydes |
publisher |
Odessa I. I. Mechnikov National University |
series |
Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
issn |
2304-0947 2414-5963 |
publishDate |
2017-09-01 |
description |
Reaction of tin tetrachloride in a 2-propanol solution and 2-(7-bromo-2-oxo-5-phenyl-3H- 1,4-benzodiazepin-1-yl)acetohydrazide (“gidazepam”, hydazepam – HHy) made it possible to obtain for the first time the corresponding tin coordination compound [Sn(HHy)Cl4] (I). A synthetic technique of the template synthesis has been developed and a novel coordination compounds [Sn(HHySl)Cl3] (II), [Sn(HHySlNO2)Cl3] (III), [Sn(HHy2Nf)Cl3] (IV), [Sn(HHy2NfBr)Cl3] (V) in the systems HHy–(HSl, HSlNO2, H2Nf, H2NfBr)–SnCl4–2-propanol, where HSl is 2-hydroxybenz-, HSlNO2 – 2-hydroxy-5-nitrobenz-, H2Nf – 1-hydroxy- 2-naphth-, H2NfBr – 4-bromo-1-hydroxy-2-naphth-aldehydes, have been synthesized. They are crystalline substances readily soluble in DMF and acetonitrile and moderately soluble in ethanol. The composition and structure of the complexes were confirmed by a number of physicochemical methods: elemental analysis, electrical conductivity, mass spectrometry, IR spectroscopy and thermogravimetry. The measurement of the electrical conductivity of solutions of the I−V in DMF has shown that they all are non-electrolytes. It was found by the thermogravimetric method that the thermolysis of complexes I−V proceeds uniformly and is stepwise in nature. The presence of peaks of molecular ions of the corresponding hydrazones in the mass spectra of complexes II−V obtained by template synthesis confirmed the formation of these hydrazones and the participation in coordination to the Sn4+ ion in the reaction course. Tin(IV) coordination polyhedron in all complexes is the octahedron formed by: four chlorine atoms, the nitrogen atom of the hydrazide amino group and the oxygen atom of the ligand carbonyl group in I; three chlorine atoms, azomethine nitrogen atom and two oxygen atoms of the carbonyl and deprotonated hydroxy group of the ligand in II−V. |
topic |
тетрахлорид стануму, гідазепам, гідразони, координаційні сполуки, темплатний синтез |
url |
http://heraldchem.onu.edu.ua/article/view/109384 |
work_keys_str_mv |
AT iiseifullina coordinationcompoundsoftinivwithhydazepamandproductsofitscondensationwitharylaldehydes AT gvyalovskiy coordinationcompoundsoftinivwithhydazepamandproductsofitscondensationwitharylaldehydes AT imrakipov coordinationcompoundsoftinivwithhydazepamandproductsofitscondensationwitharylaldehydes AT vipavlovsky coordinationcompoundsoftinivwithhydazepamandproductsofitscondensationwitharylaldehydes |
_version_ |
1725615376734093312 |