The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers
The aim of this study was the estimation of clinical importance markers of renal damage at surgical treatment of nephrolithiasis. We studied results of operations in 110 patients with nephrolithiasis. The study presents new candidates for biochemical markers of acute kidney injury and renal intersti...
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Saratov State Medical University
2010-09-01
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| Series: | Саратовский научно-медицинский журнал |
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| Online Access: | http://www.ssmj.ru/system/files/201003_708_715.pdf |
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doaj-6f3cbbfa7ba248dd80dd1e6be38ac4b82021-07-02T08:38:34ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182010-09-0163708715The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers Rossolovsky A.N.Glybochko P.M.Popkov V.M.Polozov A.B.Ponukalin A.N.Zakharova N.B.Berezinetz O.L.Blumberg B.I.The aim of this study was the estimation of clinical importance markers of renal damage at surgical treatment of nephrolithiasis. We studied results of operations in 110 patients with nephrolithiasis. The study presents new candidates for biochemical markers of acute kidney injury and renal interstitial fibrosis, with potentially high sensitivity and specificity. In this study were measured the concentrations of these biomarkers in urine. We suggested, that increased concentrations molecular mediators of renal damage (L2, IL-18) and interstitial fibrosis (MCP-1, TGFp, IGF1) in the patients with nephrophibrosis and strongetubulointerstitial injury, saved long-time period after operation, has been shown of progression chronic kidney disease http://www.ssmj.ru/system/files/201003_708_715.pdfinterstitial fibrosismediators of acute kidney injury and nephrophibrosisnephrolithiasis |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
Rossolovsky A.N. Glybochko P.M. Popkov V.M. Polozov A.B. Ponukalin A.N. Zakharova N.B. Berezinetz O.L. Blumberg B.I. |
| spellingShingle |
Rossolovsky A.N. Glybochko P.M. Popkov V.M. Polozov A.B. Ponukalin A.N. Zakharova N.B. Berezinetz O.L. Blumberg B.I. The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers Саратовский научно-медицинский журнал interstitial fibrosis mediators of acute kidney injury and nephrophibrosis nephrolithiasis |
| author_facet |
Rossolovsky A.N. Glybochko P.M. Popkov V.M. Polozov A.B. Ponukalin A.N. Zakharova N.B. Berezinetz O.L. Blumberg B.I. |
| author_sort |
Rossolovsky A.N. |
| title |
The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| title_short |
The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| title_full |
The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| title_fullStr |
The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| title_full_unstemmed |
The differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| title_sort |
differential approach to estimation of renal damage in the patients with nephrolithiasis by means of noninva-sive markers |
| publisher |
Saratov State Medical University |
| series |
Саратовский научно-медицинский журнал |
| issn |
1995-0039 2076-2518 |
| publishDate |
2010-09-01 |
| description |
The aim of this study was the estimation of clinical importance markers of renal damage at surgical treatment of nephrolithiasis. We studied results of operations in 110 patients with nephrolithiasis. The study presents new candidates for biochemical markers of acute kidney injury and renal interstitial fibrosis, with potentially high sensitivity and specificity. In this study were measured the concentrations of these biomarkers in urine. We suggested, that increased concentrations molecular mediators of renal damage (L2, IL-18) and interstitial fibrosis (MCP-1, TGFp, IGF1) in the patients with nephrophibrosis and strongetubulointerstitial injury, saved long-time period after operation, has been shown of progression chronic kidney disease |
| topic |
interstitial fibrosis mediators of acute kidney injury and nephrophibrosis nephrolithiasis |
| url |
http://www.ssmj.ru/system/files/201003_708_715.pdf |
| work_keys_str_mv |
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