Galectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPARγ) in mice
Abstract Galectin-1 contains a carbohydrate-recognition domain (CRD) as a member of the lectin family. Here, we investigated whether galectin-1 regulates adipogenesis and lipid accumulation. Galectin-1 mRNA is highly expressed in metabolic tissues such as the muscle and adipose tissues. Higher mRNA...
Main Authors: | Jung-Hwan Baek, Da-Hyun Kim, Jaegyeong Lee, Seok-Jun Kim, Kyung-Hee Chun |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-020-03367-z |
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