Synaptosomes: new vesicles for neuronal mitochondrial transplantation

Synaptosomes: new vesicles for neuronal mitochondrial transplantation

Abstract Background Mitochondrial dysfunction is a critical factor in the onset and progression of neurodegenerative diseases. Recently, mitochondrial transplantation has been advised as an innovative and attractive strategy to transfer and replace damaged mitochondria. Here we propose, for the firs...

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Bibliographic Details
Main Authors: Pasquale Picone, Gaetana Porcelli, Celeste Caruso Bavisotto, Domenico Nuzzo, Giacoma Galizzi, Pier Luigi San Biagio, Donatella Bulone, Marta Di Carlo
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Nanobiotechnology
Subjects:
Synaptosomes
Mitochondria
Neurodegeneration
Delivery system
Mitochondrial transplantation
Online Access:https://doi.org/10.1186/s12951-020-00748-6

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