Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors

Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors

The aim of the study was to explore the effectiveness of electrochemotherapy (ECT) during the treatment of melanoma patients with BRAF inhibitors. Its effectiveness was tested on BRAF mutated and non-mutated melanoma cells in vitro and in combination with BRAF inhibitors.

Bibliographic Details
Main Authors: Dolinsek Tanja, Prosen Lara, Cemazar Maja, Potocnik Tjasa, Sersa Gregor
Format: Article
Language:English
Published: Sciendo 2016-09-01
Series:Radiology and Oncology
Subjects:
electrochemotherapy
braf inhibitors
vemurafenib
melanoma
Online Access:https://doi.org/10.1515/raon-2016-0042
Description
Summary:The aim of the study was to explore the effectiveness of electrochemotherapy (ECT) during the treatment of melanoma patients with BRAF inhibitors. Its effectiveness was tested on BRAF mutated and non-mutated melanoma cells in vitro and in combination with BRAF inhibitors.
ISSN:1581-3207

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