Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?
APOBEC proteins appeared in the cellular battle against HIV-1 as part of intrinsic cellular immunity. The antiretroviral activity of some of these proteins is overtaken by the action of HIV-1 Viral Infectivity Factor (Vif) protein. Since the discovery of APOBEC3G (A3G) as an antiviral factor, many a...
Main Authors: | Iris Cadima-Couto, Joao Goncalves |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2010-01-01
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Series: | Advances in Virology |
Online Access: | http://dx.doi.org/10.1155/2010/649315 |
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