Traditional Japanese Herbal Medicine Hochu-Ekki-to Promotes Pneumococcal Colonization Clearance via Macrophage Activation and Interleukin 17A Production in Mice

Traditional Japanese Herbal Medicine Hochu-Ekki-to Promotes Pneumococcal Colonization Clearance via Macrophage Activation and Interleukin 17A Production in Mice

Streptococcus pneumoniae may colonize the nasopharynx, and as pneumococcal colonization causes invasive diseases and the subsequent transmission, reducing bacterial burden in the nasal cavity is critical. Hochu-ekki-to (TJ-41) is a traditional Japanese herbal medicine that exerts immunomodulatory ef...

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Bibliographic Details
Main Authors: Sho Nakakubo, Soichiro Kimura, Kazuyuki Mimura, Chiaki Kajiwara, Yoshikazu Ishii, Satoshi Konno, Kazuhiro Tateda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
traditional herbal medicine
Hochu-ekki-to (TJ-41)
pneumococcal colonization
macrophage
interleukin 17
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.569158/full

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