Dehydrocostus Lactone Suppresses LPS-induced Acute Lung Injury and Macrophage Activation through NF-κB Signaling Pathway Mediated by p38 MAPK and Akt

Dehydrocostus Lactone Suppresses LPS-induced Acute Lung Injury and Macrophage Activation through NF-κB Signaling Pathway Mediated by p38 MAPK and Akt

Acute lung injury (ALI) is a severe clinical disease marked by dysregulated inflammation response and has a high rate of morbidity and mortality. Macrophages, which play diverse roles in the inflammatory response, are becoming therapeutic targets in ALI. In this study we investigated the effects of...

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Bibliographic Details
Main Authors: Yunjuan Nie, Zhongxuan Wang, Gaoshang Chai, Yue Xiong, Boyu Li, Hui Zhang, Ruiting Xin, Xiaohang Qian, Zihan Tang, Jiajun Wu, Peng Zhao
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
dehydrocostus lactone
LPS
macrophage
acute lung injury
p38MAPK
Akt
NF-κB
Online Access:https://www.mdpi.com/1420-3049/24/8/1510

Internet

https://www.mdpi.com/1420-3049/24/8/1510

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