Reduced default mode network connectivity relative to white matter integrity is associated with poor cognitive outcomes in patients with idiopathic normal pressure hydrocephalus

Reduced default mode network connectivity relative to white matter integrity is associated with poor cognitive outcomes in patients with idiopathic normal pressure hydrocephalus

Abstract Background The aim of this study was to investigate whether default mode network (DMN) connectivity and brain white matter integrity at baseline were associated with severe cognitive impairments at baseline and poor cognitive outcomes after shunt placement in patients with idiopathic normal...

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Main Authors: Shigenori Kanno, Kun-ichi Ogawa, Hiroaki Kikuchi, Masako Toyoshima, Nobuhito Abe, Kazushi Sato, Koichi Miyazawa, Ryuji Oshima, Satoru Ohtomo, Hiroaki Arai, Satoshi Shibuya, Kyoko Suzuki
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Neurology
Subjects:
Alzheimer’s disease
Default mode network
Diffusion tensor imaging
Functional magnetic resonance imaging
Idiopathic normal pressure hydrocephalus
Rey auditory verbal learning test.
Online Access:https://doi.org/10.1186/s12883-021-02389-0

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