Effect of anti-IL17 and/or Rho-kinase inhibitor treatments on vascular remodeling induced by chronic allergic pulmonary inflammation

Effect of anti-IL17 and/or Rho-kinase inhibitor treatments on vascular remodeling induced by chronic allergic pulmonary inflammation

Background and aims: Expansion and morphological dysregulation of the bronchial vascular network occurs in asthmatic airways. Interleukin (IL) -17 and Rho-kinase (ROCK) are known to act in inflammation control and remodeling. Modulation of Rho-kinase proteins and IL-17 may be a promising approach fo...

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Main Authors: Tabata M. dos Santos, Renato F. Righetti, Bianca G. Rezende, Elaine C. Campos, Leandro do N. Camargo, Beatriz M. Saraiva-Romanholo, Silvia Fukuzaki, Carla M. Prado, Edna A. Leick, Milton A. Martins, Iolanda F. L. C. Tibério
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753466620962665

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