A novel large deletion of the CYLD gene causes CYLD cutaneous syndrome in a Chinese family
Abstract Background CYLD cutaneous syndrome (CCS; syn. Brooke‐Spiegler syndrome) is a rare autosomal dominant hereditary disease characterized by multiple adnexal skin tumors including cylindromas, spiradenomas, and trichoepitheliomas. More than 100 germline mutations of the cylindromatosis (CYLD) g...
Main Authors: | Ruizheng Zhu, Jie Xu, Juan Shen, Wenru Li, Fei Tan, Changchang Li, Zhichen Wei, Yeqiang Liu, Yun Bai |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-10-01
|
Series: | Molecular Genetics & Genomic Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/mgg3.1441 |
Similar Items
-
Potential role for the tumor suppressor CYLD in brain and notochord development
by: Te Li, et al.
Published: (2021-06-01) -
CYLD Promotes Apoptosis of Nasopharyngeal Carcinoma Cells by Regulating NDRG1
by: Lin Y, et al.
Published: (2020-10-01) -
Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax
by: Wu Xuefeng, et al.
Published: (2011-08-01) -
Multiple rubbery nodules on the scalp
by: Astrid Herzum, MD, et al.
Published: (2021-02-01) -
The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGF Signaling
by: Athanasios Pseftogas, et al.
Published: (2020-07-01)